Conduct NIH-funded rodent research studies focusing on Alzheimer's and metabolic dysregulation in Down Syndrome mouse models. Responsibilities include running experiments, processing biological samples, analyzing data, and contributing to research publications.
Requirements summary
Requires a Bachelor's or Master's degree in science and mandatory experience with rodent handling and small animal surgery. Preferred candidates have experience with genotyping, RNAscope, and various protein assays.
We seek a talented and motivated Research Associate I to assist in conducting an NIH-funded study at the Icahn School of Medicine at Mount Sinai examining a new mechanism and therapy for comorbid health problems, including Alzheimer’s disease, metabolic dysregulation, and more, in mouse models of Down Syndrome.
The Research Associate is an entry or mid-level researcher, responsible for conducting and assisting in rodent research studies under the supervision of Dr.
Ki Goosens and a postdoc in the Institute for Translational Medicine and Pharmacology at Mount Sinai.
The individual will conduct studies in mice.
Primary responsibilities will include running experiments, collecting and processing tissues and blood samples, and running ELISAs and other assays to measure specific biomarkers.
The individual will also organize and analyze data, help prepare research articles for publication, order reagents, perform tasks to maintain lab safety, and arrange data to meet archiving requirements.
The individual will also present data in lab meetings, department retreats, and, potentially, at scientific conferences.
Experience with genotyping of transgenic mice, performing RNAscope on different tissues, and running ELISAs, immunohistochemistry and/or Western blot is preferred.
Experience with small animal surgery and rodent handling is required.
Familiarity with multiple tissues/organ systems (brain, adipose, bone, etc.) a plus.
Candidates must be comfortable interacting with people, work well in a team, and have an interest in translational science spanning the brain and periphery.
Candidates should also be organized, able to troubleshoot or problem-solve, capable of meeting deadlines, and interested in actively contributing to a fast-paced, dynamic project.
The majority of the individual’s time and effort will be allocated to conducting the funded study as described above, but the individual may also assist with other ongoing lab projects as needed.
The position provides an excellent opportunity for training, with likely authorship on papers and abstracts, and can serve as a stepping stone to graduate school or medical school, but it could also provide a long-term opportunity to work as a laboratory scientist.
Candidates who can make at least two full years of commitment to this project are required.
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