Job detail

Research Associate I - Cancer Genetics and Epigenetics

City of Hope

#Flow Cytometry #Immunology #CRISPR #Mammalian Cell Culture #Mouse Models #Molecular Biology #Biochemistry #Epigenetics #Western Blot

Quick overview

Perform in vitro and in vivo research experiments to study transcription regulation and RNA metabolism. Maintain accurate records of methodology and results while analyzing and graphing data for lab presentations.

Requirements summary

Requires a Bachelor's degree in biological sciences with 0-2 years of laboratory experience. Preference is given to candidates with experience in molecular biology techniques, cell culture, and mouse models.

bachelor degreeData AnalysisMouse ModelsMolecular BiologyWestern BlotBiochemistryMammalian Cell CultureFlow CytometryMolecular CloningRT-qPCRRNA SplicingChromatin BiologySingle-cell TranscriptomicsCRISPR-based Genomic ScreenRNA Modification

Job description

Join the forefront of groundbreaking research at City of Hope where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses.
Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.
Dr.
Yanzhong Yang laboratory in the Department of Cancer Genetics and Epigenetics at the Beckman Research Institute of City of Hope Cancer Center is looking for a Research Associate I to support one or more of the ongoing projects studying transcription regulation and RNA metabolism in normal development and human diseases, such as neurological disorder, immunology, and cancer.
In particular, the Yang lab utilizes biochemistry, molecular biology, CRISPR-based genomic screen, single-cell transcriptomics, and genetically modified mouse models to investigate the role of protein arginine methylation in the regulation of chromatin biology, RNA splicing, and RNA modification in mammalian cells.
Learn more about Dr.
Yang’s lab here.
As a successful candidate, you will: Utilize established protocols to perform a variety of research experiments, both in vitro with cell lines and in vivo with mouse models.
Record and validate results for accuracy and completeness.
Develop techniques and expertise relevant to the laboratory’s research projects.
Maintain thorough and accurate records of methodology and results.
Analyze, compile, and graph data to present at lab meetings.

Your qualifications should include

Bachelor’s degree in biological sciences. 0-2 years of research/laboratory experience.

Preferred Qualifications

Experience with biochemical and molecular biology experiments, such as mammalian cell culture, Western blot, molecular cloning, RT-qPCR, et al. Experience with mouse models and flow cytometry is a plus. A desire to work in a collaborative, interdisciplinary lab environment that values communication, initiative, professionalism and teamwork.

Additional Information

COH employees may apply for a transfer or promotion to job openings for which they meet the minimum qualifications if they meet the following criteria: Employed at COH in current role for at least 6 months, unless otherwise stipulated in an applicable collective bargaining agreement. Are in good standing and have no current performance issues. City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location. City of Hope is an equal opportunity employer. To learn more about our Comprehensive Benefits, please CLICK HERE.