Job detail

Project Scientist - Ajami Lab - Department of Neurology

Cedars-Sinai

#ALS #Neuroscience #Immunology #Academic Research #Cedars-Sinai #Spatial Genomics #Neurodegeneration #Neuroinflammation #iPSC

Quick overview

The Project Scientist will lead research projects on immune mechanisms driving neurodegeneration, specifically focusing on ALS and microglial biology. Responsibilities include managing day-to-day lab operations, analyzing complex genomic data, and contributing to publications and grant proposals.

Requirements summary

A PhD or MD/PhD in Immunology, Neuroscience, or a related field is required, along with completed postdoctoral training. Candidates must demonstrate expertise in ALS research, a strong publication record, and experience with iPSC-derived systems and in vivo mouse models.

postgraduate degreeAnalytical SkillsData InterpretationQuantitative AnalysisMouse ModelsLab OperationsSpatial GenomicsNeuroinflammationCITE-seqMicrogliaALS ResearchSingle-cell GenomicsIntegrin BiologyECM SignalingiPSC-derived SystemsMyeloid BiologyCODEX/PhenoCycler

Job description

Are you ready to be a part of breakthrough research? Take action now by applying to this great opportunity!

Cedars-Sinai offers scientists unparalleled access to ground breaking technologies, facilities, and resources for conducting research related to an impressive range of diseases and disorders, from cancer, cardiology, and digestive diseases, to genetics, genomics, neurosciences, and women's health.

Dr. Bahareh Ajami invites you to consider this Project Scientist opportunity to join her dynamic team!

About the Team

The Ajami Lab is establishing a new research program at Cedars-Sinai focused on immune mechanisms driving neurodegeneration, with a particular emphasis on ALS and microglial biology.

About the Role

The Project Scientist works independently and in cooperation with the Principal Investigator to accomplish significant contributions to a research or project in any academic field.
The incumbent may be an ongoing member of a research team or may be employed for a limited period of time to contribute high-level skills to a specific research program.
Project Scientists are not required to carry out independent research or to develop an independent research reputation and do not have teaching responsibilities.
Ordinarily, the Project Scientist title will carry out research or creative programs as well as administration of day-to-day lab operations with supervision by a member of the Professorial Series.
This position is supported by a newly awarded NIH R01 investigating α5 integrin as a molecular switch regulating microglial and peripheral immune cell transitions in ALS.

The successful candidate will lead projects integrating

Mouse models of ALS (e.g., mSOD1, conditional knockouts)
Human iPSC-derived microglia and macrophage systems
Single-cell and spatial genomics (CITE-seq, CODEX/PhenoCycler)
Mechanistic studies of ECM–integrin signaling in neuroinflammation

Primary

Duties and Responsibilities

May assist in preparation of grant proposals, submissions, publications and presentations, but is not responsible for generating grant funds.