Research Associate, Neurology

Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We’re pioneers in RNA-targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. With multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals.

At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know that our success is a direct result of the exceptional talents and dedication of our employees.

With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money and energy into making our onsite, hybrid and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive.

We’re building on our rich history, and we believe our greatest achievements are ahead of us. If you’re passionate about the opportunity to have meaningful impact on patients in need, we invite you to apply and join us. Experience and contribute to our unique culture while you develop and expand your career!

Research associate, neurology

SUMMARY

We are seeking a motivated and skilled individual to join our Neurology Research group and participate in drug discovery for rare and severe disorders with high unmet medical need. Key responsibilities include administration of antisense oligonucleotides (ASOs), tissue sample processing, data collection, and analysis. The successful candidate will have demonstrated aptitude for laboratory work with a strong commitment to the scientific process and will be capable of working independently in a fast-paced environment.

Responsibilities

• Contribute to in vivo studies in wild-type and transgenic rodents to screen drug compounds for efficacy and tolerability, including preparing dosing solutions, dosing compounds, and performing necropsies
• Generate biochemical analyses in the wet lab using techniques such as RT-qPCR and western blotting
• Laboratory-based experimental research, including but not limited to RNA extraction, qPCR, and small rodent surgeries