Johnson & Johnson Innovative Medicine
Location
Spring House, Pennsylvania
The Scientist will design and execute in vitro experiments to validate and characterize new therapeutic agents for prostate cancer. They are responsible for generating pre-clinical data packages to support IND readiness for First-In-Human studies.
Requires a B.S. with 3+ years or an M.S. with 2+ years of experience in cancer biology and drug discovery. Proficiency in cell biology techniques, assay development, and software like GraphPad Prism and FlowJo is essential.
About Oncology Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Our Oncology team is focused on the elimination of cancer by discovering new pathways and modalities to finding treatments and cures. We lead where medicine is going and need innovators with an unwavering commitment to results. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at https://www.jnj.com/innovative-medicine We are searching for the best talent for Scientist, Biological Research - Oncology for Spring House, PA.
The Scientist will join a drug discovery team developing groundbreaking and best-in-class therapeutics for the treatment of prostate cancer. They will be a key contributor towards advancing research programs through various stages of preclinical drug discovery. This is a laboratory-based position requiring high productivity, effective and frequent collaboration with colleagues within the oncology group and other various cross-functional groups in the organization. This position requires versatility, strong communication skills, and ability to work in a fast-paced environment and high-level alignment with the Team leadership. Key Responsibilities: In this role, you will: Design and execute sophisticated in vitro experiments, and interpret data for validation and characterization of new therapeutic agents and targets to progress programs Support the generation of comprehensive and well-designed pre-clinical data packages in support of various programs, including for IND readiness for First-In-Human (FIH) studies Routinely perform cell biology techniques. Experience in cell culture, characterization of cell lines/tissue lysates by western blotting/qPCR/etc, cell proliferation assays including Incucyte-based assays, flow cytometry/FACS, CRISPR gene knockout and Lentiviral transduction of stable cell lines, cell imaging and other functional assays, etc. is needed. Analyze, prepare, and present data to internal stakeholders and project teams Work independently and perform multiple experiments simultaneously to generate robust data packages and align with scientific strategies and demands. Contribute to various projects outside of their own, and collaborate with team members from all relevant functions Keep up to date with the literature related to the field of prostate cancer Demonstrate clear and professional verbal and written communication Qualifications / Requirements: Required: An M.S. with at least 2 years of relevant experience or a B.S. with at least 3 years of relevant experience, performing progressively advanced duties at the Associate Scientist level, or the equivalent training/experience Strong cell biology and assay development skills are required A robust background in cancer biology and drug discovery is required Previous experience screening and characterizing biologic and small molecule leads is required Proficiency with software such as GraphPad Prism, FlowJo, and Microsoft Office is required Detail-oriented, with strong problem-solving skills, attention to detail, excellent organizational and record-keeping skills Preferred: · Experience in Prostate cancer research is preferred. Intellectually curious and well-informed about the latest scientific advances in the field Demonstration of creativity and novel approaches to solving scientific problems Excellent interpersonal skills with the ability to interact effectively with others, internally and externally Excellent oral and written communication skills. Able to effectively present scientific data and concepts diverse audiences. Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via , internal employees contact AskGS to be directed to your accommodation resource. If you are under 18 years of age you (the candidate) may need to obtain the necessary working papers or other documentation required by state law to start the assignment, as well as get a parent’s consent for the background check #LI-Onsite Required Skills: Preferred Skills: Analytical Reasoning, Biological Sciences, Communication, Data Analysis, Data Compilation, Data Savvy, Design of Experiments (DOE), Drug Discovery Development, Execution Focus, Laboratory Experiments, Molecular Diagnostics, Pharmaceutical Microbiology, Product Knowledge, Project Management, Report Writing, Scientific Research, Technologically Savvy, Troubleshooting At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at Do Not Sell or Share My Personal Information Limit the Use of My Personal Information
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