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Senior Clinical Research Associate

ICON plc·Washington, District of Columbia

$110,520 - $138,150/yr·Full Time·Remote Ok·Remote friendly·5-10 yrs
·Posted 4 days ago
Practice for this role

About the role

The Senior CRA is responsible for managing investigative sites and performing monitoring visits to ensure data integrity and subject safety in Oncology clinical trials. This includes facilitating communication between the client and sites, managing essential documents, and ensuring inspection readiness.

Senior Clinical Research Associate - Oncology - Washington DC

ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.

As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.

The Sr.

Clinical Research Associate (Sr.

CRA) will be responsible for performing investigative site management and monitoring activities throughout the clinical trial lifecycle.

This Sr.

CRA role will support the client's Oncology clinical trials to ensure data integrity, subject safety, and inspection readiness at the clinical investigative sites.

Responsibilities

  • Perform site management activities to support the client's Oncology site success and maintain a continuous state of inspection readiness
  • Act as the primary contact and facilitate efficient communications between the client's clinical trial team and the sites
  • Perform remote and on-site monitoring/co-monitoring visits (Site Qualification Visits, Site Initiation Visits, Interim Monitoring Visits and Close-Out Visits) to ensure data integrity and subject safety in the client's trials
  • May perform oversight activities to assess monitoring quality and train/mentor less experienced CRAs
  • Promptly document monitoring activities and submit/approve visit reports
  • Manage site essential document collection and TMF reconciliation with site files
  • Support sites with local Institutional Review Board (IRB)/Ethics Committee (EC) submissions and confirm approvals
  • Regularly review site Key Risk Indicator (KRI) metrics, issues and action items to detect trends and ensure prompt resolution
  • Independently determine root causes and develop/implement site Corrective Action and Preventive Action (CAPA) plans
  • Deliver training to ensure sites comply with the protocol, Standard Operating Procedures (SOPs), Good Clinical Practices (GCPs) and regulations
  • Support sites and the client's regulatory inspections
  • Contribute to site identification; drive site feasibility and qualification progress; and support site activation activities
  • Lead site engagement initiatives and foster relationships with key Oncology sites and networks

Qualifications

  • Bachelor’s degree (scientific field preferred)
  • 5+ years monitoring clinical trials independently conducting on-site and remote monitoring visits. Atleast 2 years monitoring solid tumor clinical trials.
  • 1+ years early development trial experience
  • Solid tumor clinical trial experience is required
  • Experience utilizing Veeva systems is highly preferred
  • Demonstrated experience developing/maintaining site relationships and securing compliance
  • Expertise in GxPs and Oncology monitoring techniques (including Risk-Based Monitoring) and terminology
  • Experience collaborating with sites from initial engagement through close-out phases
  • Experience activating sites
  • Experience training site staff
  • Experience supporting sites and/or sponsors in regulatory inspections
  • Experience working within a Functional Services (or in-house) monitoring model is preferred
  • Willing to travel up to 75%

Employment with ICON is contingent upon having the legal right to work in the country where the role is based.

Rewards & Benefits

ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.

Benefits

may include:

  • Competitive base salary and performance related incentives
  • Health and wellbeing programmes including medical, dental, and vision coverage where applicable
  • Retirement and pension plans
  • Life assurance and disability coverage
  • Employee assistance programmes and wellbeing resources
  • Learning and development opportunities through structured training and career pathways

Benefits

may vary depending on role and location.

Visit our careers site [https://careers.iconplc.com/benefits] to read more about the benefits ICON offers.

Inclusion and Accessibility

ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.

If you require reasonable accommodations during the recruitment process, please let us know or submit a request here [https://careers.iconplc.com/reasonable-accommodations].

Salary Range

$110,520.00-$138,150.00

Are you a current ICON Employee? Please click here [https://wd3.myworkday.com/icon/d/task/1422$1235.htmld] to apply

Requirements

Candidates must have a bachelor's degree and over 5 years of independent clinical trial monitoring experience, including at least 2 years in solid tumor trials. Proficiency in GxPs, Oncology monitoring techniques, and experience with Veeva systems is highly preferred.

  • bachelor degree
  • Data Integrity
  • Regulatory Inspections
  • GCP Compliance
  • Site Management
  • CAPA Implementation
  • Clinical Monitoring
  • Risk-Based Monitoring
  • Site Activation
  • Oncology Monitoring
  • IRB/EC Submissions
  • Veeva Systems
  • TMF Reconciliation

Posting details

Employment type
Full Time
Work arrangement
Remote Ok
Experience
5-10 yrs
Salary
$110,520 - $138,150/yr
Locations
Washington, District of Columbia; Blue Bell, South Dakota
Posted
Jul 24, 2026
Application
Employer website
IP

Hiring organization

ICON plc

Since our foundation in Dublin, Ireland in 1990, our mission has been to help our clients to accelerate the development of drugs and devices that save lives and improve quality of life. We do this by delivering best in class information, solutions and performance, with an...

Salary listed on 16 jobs
IndustryBiotechnology Research
TypePublic Company
Size10,001+ employees
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Market context

Senior CRA roles in DC are selective

In the District of Columbia, Senior Clinical Research Associate roles are typically driven by ongoing oncology and clinical trial activity, with employers looking for experienced monitors who can work independently. This role is competitive because it requires a bachelor’s degree, over 5 years of monitoring experience, and at least 2 years in solid tumor trials, with GxPs, oncology monitoring, and Veeva experience preferred. Review the AI-summarized requirements and benefits here to save research time, then tailor your application to highlight trial types, monitoring scope, and systems experience.

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