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Molecular Technologist I-III

Tempus AI·Minneapolis, Minnesota

Full Time·On Site·2-5 yrs·Posted 17 days ago
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About the role

The Molecular Technologist performs high-complexity clinical molecular testing, including sample accessioning, DNA extraction, and PCR testing. They also contribute to assay development, validation, and quality assurance activities to support pharmacogenomics operations.

Passionate about precision medicine and advancing the healthcare industry?

Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.

Position Overview

OneOme is seeking a Molecular Technologist to work closely with laboratory staff and cross-functional teams in support of our pharmacogenomics testing operations in Minneapolis.

This role is responsible for several phases of the testing workflow, including sample accessioning, DNA extraction, real-time PCR, and data analysis. The Molecular Technologist performs high-complexity clinical molecular testing in accordance with established procedures, quality standards, and regulatory requirements.

In addition to routine clinical testing, this position will contribute to assay development and validation, quality assurance and quality control activities, and other laboratory initiatives as assigned. The ideal candidate will bring strong technical expertise, excellent attention to detail, effective communication skills, and the ability to work both independently and collaboratively in a fast-paced environment. This role is expected to support operational needs that include weekend shifts.

Responsibilities

  • Perform sample accessioning, DNA extraction, PCR testing, and data review according to standard operating procedures
  • Conduct high-complexity clinical molecular testing in compliance with applicable regulatory and quality standards
  • Perform quality control and quality assurance activities, including maintenance of
  • associated records, monthly and annual reviews, and internal audits
  • Support laboratory development activities, including new method and assay development, workflow and process optimization, analytical validations, and software verification testing
  • Develop written technical and scientific content for procedures, policies, whitepapers, and peer-reviewed publications
  • Assist as needed with non-laboratory functions, including clerical duties, inventory control, client service activities, and other assigned responsibilities
  • Collaborate effectively with laboratory staff and other departments to support operational excellence
  • Maintain flexibility to support scheduled weekend coverage as needed
  • Required Qualifications
  • Master’s or Bachelor’s degree in medical technology, clinical laboratory science, or a related chemical, physical, or biological field
  • Educational background from an accredited institution totaling at least 60semester hours, or equivalent, from an accredited institution that, at a minimum, includes either:

24 semester hours of medical laboratory technology courses; or

24 semester hours of science courses that include: 6 semester hours of chemistry;

6 semester hours of biology; and

12 semester hours of chemistry, biology, or medical laboratory technology in any combination.

Minimum of 1 to 2+ years of post-baccalaureate (post-BS degree) clinical experience within a high-complexity CAP/CLIA-certified laboratory environment

  • At least 6 to 12 months of hands-on expertise in molecular techniques, including nucleic acid extraction
  • Excellent communication skills
  • Ability to work with others to plan and carry out scientific programs.
  • Self-driven and works well in an interdisciplinary team with minimal direction
  • Strong desire to build products that will save lives and change the course of patient care
  • Impeccable attention to detail.

Preferred Qualifications

  • ASCP certification, or eligibility for certification in a related specialty
  • Prior experience in a CLIA laboratory environment
  • 4 years+ of experience performing high-complexity testing
  • Experience with laboratory automation and liquid handling systems, in-house assay development, and validation activities including primer and probe design, assay optimization, and troubleshooting

Minnesota: $23-$30/hr

The expected salary range above is applicable if the role is performed from Minnesota and may vary for other locations (Illinois, California, Colorado, New York). Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.

We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

Requirements

Requires a Bachelor's or Master's degree in medical technology or a related biological science with 1-2+ years of clinical experience in a CAP/CLIA laboratory. Candidates must have hands-on expertise in molecular techniques and nucleic acid extraction.

  • bachelor degree
  • postgraduate degree
  • Quality Control
  • Quality Assurance
  • Data Analysis
  • Inventory Control
  • Technical Writing
  • Real-time PCR
  • DNA Extraction
  • Assay Development
  • Analytical Validation
  • Software Verification Testing
  • Sample Accessioning
  • Clinical Molecular Testing

Posting details

Employment type
Full Time
Work arrangement
On Site
Experience
2-5 yrs
Location
Minneapolis, Minnesota
Posted
Jul 10, 2026
Application
Employer website
TA

Hiring organization

Tempus AI

Tempus is a technology company advancing precision medicine through the practical application of artificial intelligence in healthcare. With one of the world’s largest libraries of multimodal data, and an operating system to make that data accessible and useful, Tempus provides...

Salary listed on 4 jobs
IndustryBiotechnology Research
TypePublic Company
Size1,001-5,000 employees
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Market context

Minnesota molecular technologist market context

In Minnesota, Molecular Technologist I-III roles are typically in steady demand at clinical laboratories supporting molecular diagnostics and other high-complexity testing. These positions are competitive because employers usually look for a relevant bachelor’s or master’s degree, CAP/CLIA lab experience, and hands-on molecular techniques such as nucleic acid extraction. Review the AI-summarized requirements and benefits on this platform to quickly compare fit, then tailor your application to specific assay experience and quality-control work.

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