City of Hope·Duarte, California
Support genomics workflows including nucleic acid extraction and library preparation for Illumina, PacBio, and 10x Genomics platforms. Maintain detailed laboratory records and assist in the optimization and validation of new genomics workflows.
Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses.
Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.
We are seeking a highly motivated Research Assistant II to join the Integrative Genomics Core.
You will support a wide range of genomics workflows, including next-generation sequencing (NGS) library preparation, nucleic acid extraction, and quality control processes.
The Integrative Genomics Core provides comprehensive genomics services to support cutting-edge biomedical research.
Leveraging advanced platforms such as Illumina, PacBio, Nanopore, and 10x Genomics, the core enables a broad range of genomic and epigenomic applications.
These technologies empower investigators to explore complex biological systems, from cancer genomics to translational and precision medicine studies, within a highly collaborative, service-oriented environment.
As a successful candidate, you will: · Perform DNA and RNA extraction, quantification, and quality control · Prepare libraries for next-generation sequencing using Illumina, PacBio (SMRT sequencing), and 10x Genomics platforms · Execute high-throughput workflows with attention to consistency and quality · Track samples and metadata using laboratory information management systems FileMaker · Maintain accurate and detailed laboratory records in accordance with core facility standards · Assist in method development, optimization, and validation of new genomics workflows under supervision of core scientists · Communicate effectively with core scientists regarding sample requirements, project status, and results
Requires a Bachelor's degree in molecular biology or genetics with 2+ years of experience, or a Master's degree with 1+ year of experience. Proficiency in standard molecular biology techniques and direct experience with NGS library preparation is preferred.
Market context
In California, Research Associate II roles in integrative genomics cores are typically competitive because they combine molecular biology fundamentals with hands-on next-generation sequencing library preparation. Candidates with a relevant bachelor’s plus experience, or a master’s with some experience, are often better positioned when they can show proficiency in standard molecular techniques and core-lab workflows. On this platform, job requirements and benefits are AI-summarized from the original job description, helping you review fit faster; if you apply, highlight any direct NGS library prep experience and related genomics methods.
