Mayo Clinic·Rochester, Minnesota
Administer chemotherapy, immunotherapy, and advanced cancer therapies to patients in an outpatient oncology unit. Coordinate nursing care, provide patient and family education, and collaborate with a multidisciplinary team on innovative treatments.
Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
Highlights Medical: Multiple plan options.
Delta Dental or reimbursement account for flexible coverage.
Affordable plan with national network.
Pre-Tax
Savings: HSA and FSAs for eligible expenses.
Competitive retirement package to secure your future.
The primary role of the RN in this position is administration of chemotherapeutic agents and patient education in the outpatient setting. Watch what it’s like to be a Chemotherapy Infusion RN at Mayo Clinic Orientation and Growth We are committed to helping you feel supported, prepared, and confident as you build your oncology nursing practice. Your orientation includes: 12+ hours of structured chemotherapy education 12 hours of cancer core knowledge Three months of guided, hands-on learning You’ll work side-by-side with a preceptor to build IV skills, strengthen critical thinking, and grow into the role step by step. As cancer care continues to evolve, we prepare our nurses not only for today’s patients, but for the therapies shaping the future of oncology care. It’s also an exciting time to join our team, with a 15-chair expansion planned for early 2027. The registered nurse (RN) is accountable for: Coordination of nursing care, including direct patient care, patient/family education and transitions of care. Supporting professional nursing practice across practice settings and across the continuum of care to meet the needs of the patient and family. Functioning within the Mayo Clinic Nursing Professional Practice Model, which includes accountability for planning, implementing, evaluating and communicating all phases of nursing care for assigned patients. The ANA Nursing: Scope and Standards of Practice provide a basis for the practice of the RN. Providing leadership through activities such as preceptor role, informal and formal leadership roles, and quality improvement efforts. Delegating patient care according to skill level, experience, patient acuity, fiscal accountability and availability of resources. Possessing excellent communication skills; is skillful in mentoring and teaching; and may participate on committees or projects. A subset of employees may be required to drive their personal vehicle as a part of the responsibility of their role. This role is eligible for TN sponsorship. Successful sponsorship will require state licensure and completion of the VisaScreen or equivalent certification.
Internal applicants are required to attach their three most recent performance appraisals. License and Certification (Must obtain prior to start date): Current RN license by applicable state requirements. BLS (Basic Life Support) must be valid for 90 days post start date; acceptable certifications include: American Heart Association (AHA)/ Heartcode® BLS, Military Training Network, Red Cross (CPR/AED for Professional Rescuers and Health Care Providers). Additional state licensure(s) and/or specialty certification/training as required by the work
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is.
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law". Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.
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Requires a nursing degree from an accredited program and at least one year of RN experience. Must hold a current state RN license and a valid BLS certification.
Market context
Minnesota nursing openings often reflect steady demand in senior care settings, where employers look for RNs who can support older adults and work reliably across shifts. These roles are competitive because an accredited nursing degree, an unencumbered RN license, and prior senior-population experience are common screening points; a bachelor’s degree can strengthen candidacy. Review the AI-summarized requirements and benefits on this platform to save time, then confirm your license status and tailor your application to senior-care experience.