St. Jude Children's Research Hospital·Memphis, Tennessee
Perform laboratory experiments using prescribed protocols to investigate pediatric brain tumors and neural progenitor cells. Accurately record experimental data and assist in drafting results for posters, presentations, or publications.
The Han laboratory at St. Jude Children’s Research Hospital is seeking a highly motivated Research Technologist with a strong interest in the mechanisms of brain development, brain tumors, or neurodevelopmental disorders.
Humans have the largest neocortex relative to their brain size, and its folded surface is thought to be the root of our unique mental abilities. What cellular and molecular mechanisms drive the development and evolution of this remarkable structure? How do disruptions in these mechanisms lead to neurodevelopmental disorders and brain tumors? We aim to answer these fundamental questions by investigating the neural progenitor cells that construct the brain during development.
To uncover the mechanisms regulating human neural progenitor cells, we developed the first stable and robust genetic mouse model, in which neural progenitors acquire the key features of human neural progenitors, driving the transformation of the small, smooth mouse cortex into an expanded, folded cortex. In addition to this unique and powerful animal model, we employ a broad range of approaches, including human pluripotent stem cells, brain organoids, genome editing, high-resolution imaging, single-cell sequencing, spatial transcriptomics, and proteomics. Please refer to our website (https://www.stjude.org/research/labs/han-lab.html [https://www.stjude.org/research/labs/han-lab.html]) for further information.
The immediate research project will focus on characterizing novel cellular models of a pediatric brain tumor, which have been derived from patient samples and human pluripotent stem cells. The successful candidate will work in a highly collaborative environment to investigate the mechanisms that drive tumorigenesis and to develop therapeutic approaches that target those mechanisms.
The ideal candidate will be self-motivated, organized, and enthusiastic about biomedical research. Experience in stem cells, organoid models, molecular biology, and related methodologies is desirable. Candidates with a strong desire to learn new techniques and to contribute to a collaborative research to tackle pediatric brain tumors are encouraged to apply.
To apply, please send a summary of previous research, curriculum vitae, and contact information for references to young-goo.han@stjude.org [young-goo.han@stjude.org].
• Bachelor's degree in relevant scientific area is required
• no experience required
In recognition of certain U.S. state and municipal pay transparency laws, St.
Jude is including a reasonable estimate of the compensation range for this role.
This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs.
It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case.
A reasonable estimate of the current salary range is $24.00 - $42.00 per hour for the role of Researcher - Developmental Neurobiology (Han Lab).
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St. Jude is an Equal Opportunity Employer [https://www.stjude.org/jobs/hospital/workplace-policies.html]
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Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities.
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Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St.
Jude.
A Bachelor's degree in a relevant scientific area is required, with no prior experience necessary. Experience in stem cells, organoid models, and molecular biology is highly desirable.
Market context
In Tennessee, developmental neurobiology researcher roles are typically tied to university and biomedical research settings, where demand follows active lab programs and funded projects. These positions can be competitive because employers often value hands-on experience with stem cells, organoid models, and molecular biology, even when no prior experience is required. Review the AI-summarized requirements and benefits on this platform to save time, then tailor your application to show relevant lab coursework, techniques, and research interest.