St. Jude Children's Research Hospital·Memphis, Tennessee
Conduct research on primary cilia and cilia-dependent signaling to understand their role in brain development and various neurological diseases. Utilize advanced techniques such as brain organoids, single-cell sequencing, and unique mouse models to study cellular homeostasis.
A postdoctoral position is available in the laboratory of Dr.
Young-Goo Han in the Department of Developmental Neurobiology/Neurobiology and Brain Tumor Program at St.
Jude Children’s Research Hospital.
The Han laboratory studies the biology of primary cilia and how cilia-dependent signaling regulates cell behavior in normal development and disease, with particular emphasis on brain development, brain tumors, neurodevelopmental disorders, and neurodegenerative diseases.
The Han laboratory has made important contributions to understanding the roles of primary cilia and Hedgehog signaling in neural stem cell formation, cerebellar development, medulloblastoma, neocortical growth and folding, and cilia-dependent regulation of translation and the cell cycle.
Applicants who are interested in fundamental mechanisms by which primary cilia or mitochondria control cellular homeostasis and signaling are encouraged to apply.
We use a broad range of approaches, including human pluripotent stem cells, brain organoids, genome editing, high-resolution imaging, single-cell sequencing, spatial transcriptomics, epigenomics, and proteomics, as well as a unique mouse model in which neural progenitors acquire key features of human neural progenitors, driving expansion and folding of the normally small, smooth mouse cortex.
Research areas may include: Primary cilia and compartmentalized signaling Cell and molecular mechanisms of cilia function Mitochondrial homeostasis Brain development and neural progenitor biology Brain tumor biology Neurodevelopmental and neurodegenerative disorders Qualifications Applicants should have a Ph.D., M.D., or equivalent degree and a strong background in cell biology, molecular biology, developmental biology, neuroscience, cancer biology, neurodegeneration, or a related field.
Experience in one or more of the following areas is desirable: primary cilia biology, mitochondrial homeostasis, mouse genetics, imaging, biochemistry, genomics, stem/progenitor cell biology, or disease models.
Highly motivated candidates with strong communication skills and a record of scientific productivity are encouraged to apply.
Environment St.
Jude provides an outstanding and highly collaborative research environment with exceptional core facilities and strong support for postdoctoral training and career development.
The Han laboratory offers opportunities to pursue mechanistic and conceptually innovative projects at the interface of cell biology, development, and disease.
To apply Please send: a cover letter describing research interests and career goals, a curriculum vitae, and contact information for three references to: Young-Goo Han, Ph.D.
St.
Jude Children’s Research Hospital young-goo.han@stjude.org St.
Jude is an Equal Opportunity Employer No Search Firms St.
Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities.
Please do not call or email.
All resumes submitted by search firms to any employee or other representative at St.
Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St.
Jude.
Applicants must hold a Ph.D., M.D., or equivalent degree with a strong background in cell, molecular, or developmental biology. Experience in primary cilia, mitochondrial homeostasis, or genomics is highly desirable.
Market context
In Tennessee, postdoctoral research roles in developmental neurobiology are typically most competitive at universities and research institutes that support active lab funding and collaborative projects. Candidates with a PhD in cancer biology, molecular or cellular biology, and a strong publication record stand out, especially when they also bring next-generation sequencing or single-cell genomics experience. Review the AI-summarized requirements and benefits here to save time, then tailor your application to highlight relevant publications, methods, and research fit.
