St. Jude Children's Research Hospital·Memphis, Tennessee
The role involves designing, synthesizing, and optimizing stable isotope-labeled amino acids and derivatives for protein NMR studies. Responsibilities include performing purification, maintaining synthetic chemistry equipment, and delivering reagents to the protein preparation team.
We are seeking an Associate Scientist to join our Blue Sky Protein Kinases team in the Department of Structural Biology at St.
Jude Children's Research Hospital.
The World’s Brightest Minds Always Innovate At St.
Jude Children’s Research Hospital, we know what can be achieved when the brightest scientific minds face the fewest barriers.
That’s why we provide world-class facilities.
State-of-the-art technologies.
Extraordinary support.
And a collaborative, bench-to-bedside environment where you can see, firsthand, how your science translates into survival for the children we serve.
Quite simply, at St.
Jude, we encourage you to dream big and stop at nothing when it comes to finding cures and saving children.
Key Responsibilities for this Role Design, synthesize, and optimize stable isotope–labeled amino acids and related derivatives that serve as precursors for isotope-labeled proteins used in protein NMR studies.
Perform separation, purification, and analytical characterization of amino acids.
Operate and perform routine maintenance of synthetic chemistry equipment, and manage personal synthesis schedules to ensure timely project completion.
Deliver synthesized reagents to the protein preparation team in a timely manner to meet project deadlines.
The World’s Best Stop at Nothing There’s a reason St.
Jude Children’s Research Hospital is consistently ranked on Glassdoor’s “Best Places to Work” list.
Actually, there are more than 5,500 reasons.
At our world-class pediatric research hospital, every one of our 5,500 professionals shares our commitment to making a difference in the lives of the children we serve.
There’s a unique bond when you are part of a team that will stop at nothing to advance the treatments and cures of pediatric catastrophic diseases.
The result is a collaborative, positive environment where all employees, regardless of their role, receive the resources, support, and encouragement to advance and grow their careers.
Preferred Candidate Extensive hands-on experience in multi-step (≥10 steps) gram-scale synthesis of complex compounds; experience with stable isotope–labeled compounds is highly desirable.
Strong expertise in amino acid purification and analytical methods.
Solid understanding of protein NMR applications utilizing stable isotopes.
Familiarity with cell-based (e.g., bacterial or insect) and cell-free protein synthesis systems for stable isotope–labeled protein production.
Demonstrated ability to manage multiple research projects simultaneously, maintain thorough daily documentation of experimental work, and consistently meet deadlines. Have More in Memphis Get the best of big-city amenities mixed with all the charm of a small-town feel when you live in Memphis.
From our world-renowned music scene to our eclectic mix of food and people.
Memphis is a place our employees are proud to call home.
Our region enjoys a cost of living more than 20% lower than the national average and our state places no personal income tax on wages.
Plus, Memphians spend five hours less per year in their daily commute compared to the national average.
Learn how you can “Have More in Memphis.” Minimum Education and/or Training Bachelor’s degree in a relevant scientific area. Minimum Experience 7 + years of research experience is required with a Bachelor's degree.
5 + years of research experience is required with a Master’s degree.
2 + years of research experience is required with a PhD.
Your health and well-being are important to us. That's why St. Jude Children's Research Hospital provides employees with high-quality benefits choices. We are committed to ensuring our benefits are competitive and affordable. St. Jude continues to cover medical premiums for employees and offers low additional costs for dependents. View all the benefits offered including Medical & Prescription Drug Plans, Dental Plan, Vision Plan, Financial Security, Retirement Plan, Living Well - Employee Wellness Program, Time Off Programs, Educational Benefits, Family Friendly Benefits, and Benefits Unique to St. Jude. Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $65,520 - $114,400 per year for the role of Chemistry Associate Scientist in Kalodimos Lab. Explore our exceptional benefits! St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.
Candidates must have a bachelor's degree in a scientific area with varying years of research experience depending on the degree level (7+ for BS, 5+ for MS, 2+ for PhD). Extensive hands-on experience in complex multi-step gram-scale synthesis and amino acid purification is highly desired.
Market context
Chemistry associate scientist roles in Tennessee are typically tied to active research, development, or lab-support pipelines, so candidates with strong synthesis and purification experience are often in demand. This role is competitive because the requirements emphasize hands-on multi-step gram-scale synthesis, amino acid purification, and substantial research experience by degree level. Review the AI-summarized requirements and benefits here to quickly compare fit, then tailor your application to the specific techniques and project work you have done.
