Design and execute in vitro studies to assess novel antibody-drug conjugates and optimize pharmacological and biochemical assays. Collaborate with cross-functional teams to advance programs from early discovery to preclinical development.
Company Description About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.
AbbVie Oncology Discovery is seeking a highly motivated and experienced cancer cell biologist to support drug discovery projects in our in vitro cancer biology team with a focus on antibody-drug conjugates. The candidate will work closely with a team of experienced scientists to develop and optimize key pharmacological, biochemical and cell-based assays to support multiple programs.
Key
Responsibilities: Design and execute in vitro studies to assess novel antibody-drug conjugates Analyze and interpret experiments and present data to the broader project team and group meetings. Propose relevant follow-up experiments as needed. Troubleshoot and/or optimize experimental procedures as needed to further the program goals. Contribute to the preparation of data packages for scientific publications, regulatory documents, and patent applications Work independently in a fast paced, multi-tasking environment as part of a diverse research team. Collaborate with cross-functional teams to advance programs from early discovery to preclinical development
Required: Bachelor’s Degree with 5 years of experience, or Master’s Degree with two years of experience in molecular/cellular biology, cancer biology, pharmacology or related discipline with significant research experience. Proficiency in tissue culture, cellular & biochemical in vitro assay development and molecular biology techniques (e.g Western blotting/WES, ELISA, proliferation assays, FACS, lentivirus) Background in drug discovery, pharmacology and assay development. Organizational skills and experience with computer programs, including Microsoft Excel, Powerpoint, GraphPad, FlowJo, etc.
Understanding and application of methods of antibody characterization and/or antibody-drug conjugates. Knowledge and experience with a broad range of assays to characterize targeted protein degradation Familiarity and proficiency with available genomic/transcriptomic datasets (TCGA, DepMap, CCLE etc.)
Key
Leadership
Competencies: Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance. Learns fast, grasps the 'essence' and can change the course quickly where indicated. Raises the bar and is never satisfied with the status quo. Creates a learning environment, open to suggestions and experimentation for improvement. Embraces innovation and manages to reality.
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this roleat the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on manyfactors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future. We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees. This job is eligible to participate in our short-term incentive programs. Note: No amount of pay is considered to be wages or compensation until such amount isearned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that areallocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolutediscretion, consistent with applicable law. AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable-accommodations.html
Requires a Bachelor's degree with 5 years of experience or a Master's degree with 2 years of experience in molecular/cellular biology or a related field. Proficiency in tissue culture, molecular biology techniques, and drug discovery assay development is essential.
Market context
In Illinois, cell and molecular biology roles are commonly tied to biotech, pharma, and research organizations that need hands-on assay and tissue-culture expertise. This position is competitive because it asks for both practical lab skills and drug discovery assay development, and the requirements and benefits shown here are AI-summarized from the original job description to save you research time. If you apply, tailor your resume to highlight tissue culture, molecular biology methods, and any assay development work.