Scientist (52095)
GAP SOLUTIONS INC·Montgomery County, Maryland
GAP SOLUTIONS INC·Montgomery County, Maryland
Conduct laboratory-based translational research focused on cancer drug development and diagnostics. Design and execute complex genetic and biochemical assays while collaborating with scientific staff to publish findings in peer-reviewed journals.
Conduct laboratory-based translational research with a focus on drug development for the treatment of cancer. 1 Study cultured human and animal cell lines, some of which may be derived from cancer tissue, and analyze human and/or animal tissues with and without cancer. 2 Perform a wide range of sophisticated genetic, biological, and biochemical assays, including, but not limited to DNA transfection of cells, monolayer and anchorage-independent growth assays, immuno-precipitation assays, agarose gel electrophoresis, and in vivo and in vitro kinase assays. 3 Perform confocal immune-confocal microscopy of cells 4 Perform studies that result in technical reports and information to advance cancer research. Initiate, design, and develop new projects or assays that can enable the Center for Cancer Research/Laboratory of U. Rudloff, Rare Tumor Initiative, POB, NCI to fulfill its responsibilities for advance in cancer research and development of cancer diagnostics, cancer drugs, and cancer vaccines. Serve as an authority on the tumor biology that is being studied and the assays that are being performed. Interpret results of initial analysis to reveal conclusions and shortcomings; identify pitfalls in the original choice of methods or experimental direction; redirect the study to achieve improved results. Identify the need for further investigations and/or propose change in direction of work in light of accomplishments, findings, and current and future mission objectives. Work with the scientific staff to define key questions emerging from research projects in which experimental in vitro and in vivo analysis will contribute to elucidation of impact of novel experimental therapeutics on immune cells, cancer cells, and tumors grown in mice in general, mechanisms of cell transformation, identification of molecular targets, and the development of biomarkers/biomarker signatures with potential to guide prevention, diagnosis, or treatment. Collaborate with scientists and statisticians in NCI, NIH, and extramural research institutions as appropriate, to advance the research projects and elucidation of cancer-related data. Collaborate with NIH/NCI expert staff to clarify needs and project objectives. Assists in maintaining adequate space and facilities for ongoing and projected research studies. Attend seminars within the National Institute of Health/Center for Cancer Research/Laboratory of U. Rudloff; pursue additional training, where necessary; participate in discussions at meetings. Make oral presentations at various conferences and seminars. Prepare data sets, Tables and Figures for collaborative papers prepared for publication in peer-reviewed journals; assemble and write papers for first-author publication in peer-reviewed papers. Participate in special committees, panels, and colloquia that meet to determine policy or plan activity in the field. Work documents and products related to working with laboratory personnel in designing and performing experiments, data analysis and interpretation of results Work documents and products related to initiating, designing, and developing new projects or assays that can enable the Center for Cancer Research/Rare Tumor Initiative, Dr. U. Rudloff’s Laboratory to fulfill its responsibilities for advance in cancer research and development of cancer diagnostics, cancer drugs, and cancer vaccines Work products and documents related to performing studies that result in technical reports and information to advance cancer Research Work products and documents related to working with the scientific staff to define key questions emerging from research projects in which experimental in vitro and in vivo analysis will contribute to elucidation of impact of novel experimental therapeutics on immune cells, cancer cells, and tumors grown in mice in general, mechanisms of cell transformation, identification of molecular targets, and the development of biomarkers/biomarker signatures with potential to guide prevention, diagnosis, or treatment QualificationsBasic Qualifications: Ph.D. in Biology, Life Sciences or related discipline Minimum of 2 yrs experience in a laboratory environment Research experience in immunology and/or molecular biology Expertise in mouse handling procedures including intraperitoneal intravenous injections, tumor measurements dissections; Immunologic studies including multiparameter flow cytometric processing data analysis as well as in-vitro functional assays including cell culture, stimulation, proliferations, cytokine production. Expertise in molecular studies techniques including DNA RNA extraction quantification, gel electrophoresis, western blotting, PCR and immunoprecipitation; Optical but helpful experience in other techniques include confocal microscopy. Ability to learn new techniques and teach known techniques to others Knowledge of proper laboratory techniques, disposal methods, laboratory safety procedures, and universal precautions Experience in Animal Handling: Mouse Proficiency in the use of computers and computer programs including expertise in Microsoft Office Suite (MS Word, PowerPoint, Excel)
Ability to communicate effectively, orally and in writing, with non-technical and technical staff Detail-oriented and possess strong organizational skills with the ability to prioritize multiple tasks and projects *This job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required by this position. To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. GAP Solutions provides reasonable accommodations to qualified individuals with disabilities. If you need an accommodation to apply for a job, email us at recruiting@gapsi.com. You will need to reference the requisition number of the position in which you are interested. Your message will be routed to the appropriate recruiter who will assist you. Please note, this email address is only to be used for those individuals who need an accommodation to apply for a job. Emails for any other reason or those that do not include a requisition number will not be returned. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, protected veteran status or other characteristics protected by law. This position is contingent upon contract award.
Requires a Ph.D. in Biology or Life Sciences with at least 2 years of laboratory experience in immunology or molecular biology. Must be proficient in mouse handling, flow cytometry, and various molecular study techniques.
Market context
In Maryland, Scientist roles in biology and life sciences are typically driven by research, biotech, and academic lab demand, especially for candidates with immunology or molecular biology experience. These positions are competitive because employers often look for a Ph.D., hands-on mouse handling, flow cytometry, and other molecular techniques; the requirements and benefits shown here are AI-summarized from the original job description, which can save you time reviewing postings. If you are applying, match your lab methods closely to the listed techniques and highlight specific research projects that show depth in those areas.