Cogent Scientific
Location
South San Francisco, California
Salary
$105,000 - $115,000 / YEAR
Lead in vitro discovery biology for oncology programs, focusing on target validation and candidate selection across various therapeutic modalities. Design and execute cell-based assays and mechanistic studies to characterize target engagement and mechanism of action.
Requires a PhD in Molecular Biology, Biochemistry, or a related field with 0-2 years of industry or postdoctoral experience in oncology drug discovery. Candidates must possess strong communication, collaboration, and problem-solving skills to work in a fast-paced multidisciplinary environment.
Cogent Scientific, an insourced contract research organization, is looking for the right people to accomplish our Mission: to support the life sciences industry by cultivating and empowering exceptional scientists to deliver specialized laboratory services that advance research, foster collaboration, and accelerate innovation through quality and a shared commitment to excellence. We can offer you the chance to build on your skills and knowledge while working among experts in their fields and with cutting-edge instrumentation.
We currently have a role available for an Expert Pharma Discovery Biologist.
Leading in vitro discovery biology across oncology programs, from early target validation through candidate selection, spanning multiple therapeutic modalities. Contributing to target identification and prioritization by integrating literature, pathway biology, and emerging clinical and preclinical data to nominate and validate novel therapeutic targets. Designing and executing cell-based assays to evaluate compound activity, including viability, proliferation, and apoptosis readouts across relevant tumor models. Driving mechanistic and signaling studies (e.g., Western blot, phosphoproteomics, pathway analysis) to characterize target engagement and mechanism of action. Leading target biology efforts including evaluation of target expression, antigen density, receptor internalization, intracellular trafficking, and target-dependent processing. Developing and optimizing disease-relevant in vitro models (e.g., 3D culture systems, model generation, co-culture platforms) to characterize novel modalities and enable translational studies.
PhD in Molecular Biology, Biochemistry or related field with 0-2 years of industry or relevant postdoctoral experience in oncology drug discovery or targeted therapeutics research. Excellent communication skills – verbal and written. Works well both within a team and as an individual. Demonstration of excellent team player and collaboration skills, very strong attention to detail, very strong problem-solving skills, a high level of learning agility, and the ability to work across functions. The ideal candidate will be enthusiastic and self-motivated, with the leadership and communication skills necessary to operate effectively in a fast-paced multidisciplinary environment with flexibility and an adaptable approach to goal delivery.
This is a day shift position (approx. 8a-5p local time).
Cogent Scientific provides equal employment opportunities to all applicants and does not discriminate based on any legally protected characteristic.
Additionally, if you require a reasonable accommodation during the application or interview process, please let us know.
This job posting will close by 7/6/2026 or when a candidate is identified, whichever comes first.
No additional openings are live from this employer right now.
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