St. Jude Children's Research Hospital·Memphis, Tennessee
Conduct independent research on T cell-mediated regulation of hematopoietic stem cells and bone marrow immunity using mouse models and single-cell technologies. Analyze data, publish results in peer-reviewed journals, and mentor students within a collaborative research environment.
A postdoctoral research associate position is available in the Yamashita lab.
Hematopoietic stem cells (HSCs) sustain lifelong blood production, and defects in their regulation contribute to diverse hematologic disorders, including clonal hematopoiesis, hematologic malignancies, and aplastic anemia. This project aims to define how T cell–mediated immune surveillance regulates HSC fate in the bone marrow and influences disease outcomes, ranging from immune tolerance and clonal expansion to graft-versus-leukemia activity and bone marrow failure. Using state-of-the-art mouse models, immunologic approaches, and single-cell technologies, the successful candidate will investigate the cellular and molecular mechanisms that govern immune–stem cell interactions. These studies will provide fundamental insights into hematopoietic homeostasis and uncover new therapeutic opportunities for hematologic disease.
About the lab and St.
The Yamashita Laboratory seeks to understand how hematopoietic stem cells (HSCs) maintain blood production throughout life and how their dysregulation contributes to hematologic disorders. Our research focuses on the molecular mechanisms that govern HSC survival, elimination, and immune surveillance, with the goal of identifying new therapeutic strategies for hematologic disorders, including clonal hematopoiesis, hematologic malignancies, and aplastic anemia. We are committed to providing a collaborative, supportive, and trainee-centered environment that fosters scientific rigor, creativity, and independence while helping postdoctoral fellows develop into future scientific leaders. Learn more about our research and team at https://www.stjude.org/research/labs/yamashita-lab.html [https://www.stjude.org/research/labs/yamashita-lab.html].
St.
Jude Children’s Research Hospital is a world-class research institution dedicated to pediatric cancer and other catastrophic diseases of childhood.
The first and only National Cancer Institute (NCI)-designated Comprehensive Cancer Center devoted solely to children.
Our 300 faculty work across the spectrum of basic, translational, clinical, and population science in a highly collaborative multidisciplinary environment that includes a Nobel laureate and members of the National Academy of Science and the National Academy of Medicine.
St.
Jude is ranked on Fortune Magazine’s “Best Workplaces in Health Care & Biopharma” and Glassdoor’s “Best Places to Work,” and is located in the heart of Memphis, Tennessee, a vibrant and friendly city at the historic American crossroads of music, trade, food and culture.
We are in pursuit of the brightest minds in biomedical sciences, individuals poised to contribute to our research progress. Other than access to top-quality scientists and mentors, as a postdoctoral trainee at St. Jude, you will have:
A Blend of Academic Freedom and Industrial Efficiency: Access to shared resources and facilities led by expert scientists, coupled with cutting-edge technology, accelerates research productivity.
Customized Professional and Career Growth: Experience specifically designed programs to enhance professional growth and career readiness empowering postdocs for success beyond their training. This includes access to grant writing workshops, individual development plans, teaching and mentoring opportunities, non-research career advancement programs, professional development allowance, and so much more.
Competitive Compensation: Embark on your journey with a competitive salary starting at $72,500 a year, comprehensive benefits and generous relocation assistance, reflecting our commitment to recognize and invest in talent.
A Sense of Community: St. Jude fosters a vibrant postdoc community that supports a well-balanced life. A dynamic environment promotes connections and camaraderie among postdocs from all backgrounds.
St. Jude is an Equal Opportunity Employer [https://www.stjude.org/jobs/hospital/workplace-policies.html]
St.
Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities.
Please do not call or email.
All resumes submitted by search firms to any employee or other representative at St.
Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St.
Jude.
Requires a PhD, MD, or MD/PhD in Immunology, Hematology, Stem Cell Biology, or a related field. Candidates must demonstrate research productivity and proficiency in flow cytometry, mouse handling, and molecular biology techniques.
Market context
In Tennessee, postdoctoral hematology roles are typically tied to active lab programs, grant-funded projects, and translational research settings. Competition is strongest for candidates who can show publication history, hands-on expertise in flow cytometry, mouse handling, and molecular biology, plus a clear fit with the lab’s research focus. Review the original posting carefully and tailor your application to the specific techniques and disease area; this platform’s AI-summarized requirements and benefits help you compare roles faster without reading every full description.
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