Headlands Research·Myrtle Beach, South Carolina
The role involves serving as a Sub-Investigator to ensure the safety and medical care of clinical trial participants. Responsibilities include conducting physical examinations, reviewing diagnostic results, and collaborating with the Principal Investigator to execute study protocols.
At Headlands Research, we are dedicated to enhancing clinical trial delivery within our communities.
As a leading network of advanced clinical trial sites, we leverage cutting-edge technology and exceptional support services to broaden outreach and participation.
Founded in 2018, our rapidly growing company currently operates 20+ sites across the US and Canada, with plans for further expansion.
Clinical Research | Myrtle Beach, South Carolina Continue Practicing Medicine in a Role That Values Your Clinical Expertise Are you an experienced Nurse Practitioner or Physician Assistant looking for a role where you can focus on practicing medicine - not insurance authorizations, productivity quotas, or running a busy clinic?
Headlands Research is seeking a seasoned Advanced Practice Provider to serve as a full-time Sub-Investigator at our established clinical research site in beautiful Myrtle Beach, South Carolina.
This is an exceptional opportunity for an experienced provider who enjoys building meaningful relationships with patients, values clinical autonomy, and wants to continue using their assessment, diagnostic, and medical decision-making skills every day.
Clinical research offers the opportunity to practice medicine in a different way.
Rather than seeing a high volume of patients, you'll spend meaningful time with research participants, perform comprehensive clinical evaluations, interpret diagnostic results, and help advance innovative therapies that have the potential to improve lives around the world.
Why Join Headlands Research?
Practice at the Top of Your License As the sole full-time medical provider at our Myrtle Beach site, you'll serve as the primary medical resource for a dedicated team of approximately 15-20 clinical research professionals.
You will collaborate with part-time and contract providers.
Working alongside experienced Clinical Research Coordinators, Research Assistants, Laboratory staff, the Site Director, Principal Investigators, and study sponsors, you'll play an integral role in ensuring participant safety and the successful execution of clinical trials.
While the Principal Investigator maintains overall responsibility for each clinical trial, you'll work collaboratively with the PI to deliver exceptional participant care.
Your medical expertise will help guide the clinical team, support medical decision-making, answer protocol-related clinical questions, and ensure the highest standards of quality throughout every study.
This is a highly collaborative environment where you'll never practice in isolation.
You'll be supported by an experienced research team that manages study operations, allowing you to focus on what you do best—providing excellent patient care and contributing to the advancement of new medical therapies.
Predictable Schedule & Exceptional Work-Life Balance Monday-Thursday: 7:00 AM – 4:30 PM Friday: 7:30 AM – 11:30 AM No evenings No weekends Make an Impact Beyond Individual Patients Every participant you care for contributes to the development of future treatments that may benefit thousands of patients.
Your work will directly influence the advancement of medicine while providing access to cutting-edge therapies for your local community.
About Headlands Research Headlands Research is one of the fastest-growing integrated clinical trial site networks in North America, operating more than 20 research sites across the United States and Canada.
Our mission is simple: Improve lives by advancing innovative medical therapies and making clinical research accessible to all.
We're committed to expanding access to clinical trials, increasing diversity in research, and delivering an exceptional experience for both participants and healthcare professionals.
Position: Full-Time Nurse Practitioner or Physician Assistant (Sub-Investigator) Location: Myrtle Beach, South Carolina (Onsite) Employment Type: Full-Time Regular Employee Compensation: Competitive salary based on years of clinical and research experience
Ensure the safety, well-being, and medical care of clinical trial participants throughout each study Conduct medical history reviews, comprehensive physical examinations, and protocol-required assessments Evaluate potential participants against study-specific inclusion and exclusion criteria Review laboratory results, ECGs, and other diagnostic testing Assess adverse events and provide appropriate medical care throughout study participation Maintain a thorough understanding of assigned research protocols Collaborate closely with Principal Investigators and provide day-to-day clinical guidance to Clinical Research Coordinators, Research Assistants, Laboratory staff, and other site personnel Partner with the Site Director and research team to ensure efficient, high-quality study execution Attend Investigator Meetings on behalf of the Principal Investigator when appropriate Provide limited home-based on-call availability according to site policy Maintain exceptional professionalism, communication, and attention to detail while fostering a collaborative team environment
Required Current and unrestricted Nurse Practitioner or Physician Assistant license in South Carolina (or eligible for licensure) Minimum of two years of clinical experience as a licensed Advanced Practice Provider Experience caring for adult and geriatric patients in one or more of the following settings: Internal Medicine Family Medicine Primary Care Urgent Care Emergency Medicine Strong physical assessment, diagnostic, and clinical decision-making skills Excellent communication and interpersonal skills Exceptional organizational skills and attention to detail A collaborative leadership style with a passion for working alongside multidisciplinary clinical teams Preferred Previous experience as a Sub-Investigator or Investigator in clinical research Experience working on FDA-regulated clinical trials Current Good Clinical Practice (GCP) training No prior clinical research experience is required. We provide comprehensive training to help experienced clinicians successfully transition into research while continuing to practice medicine at a high level. Why Experienced Providers Choose Clinical Research Many Advanced Practice Providers reach a point in their careers where they're looking for a role that allows them to continue practicing medicine while enjoying greater work-life balance, more meaningful patient interactions, and the opportunity to make a broader impact on the future of healthcare. At Headlands Research, you'll continue using your clinical expertise every day—not simply completing paperwork. You'll evaluate patients, perform physical examinations, interpret clinical findings, collaborate with an experienced multidisciplinary team, and help bring innovative treatments to patients who need them most. If you're looking for a position where your clinical judgment is trusted, your schedule is predictable, your expertise is valued, and your work contributes to the future of medicine, we'd love to meet you. Headlands Research will never ask a candidate for personal identifiable information (date of birth, social security number, driver’s license information, etc) via email or messenger tools, or for a financial deposit of any kind. Headlands Research is an Equal Opportunity Employer. We do not discriminate on the basis of race, color, religion, age, sex, national origin, disability status, genetic information, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state, or local laws. Need Assistance? Headlands Research is committed to providing access and reasonable accommodation in its employment for individuals with disabilities. To request disability accommodation in the application process, contact recruiting@headlandsresearch.com for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.
Candidates must hold an unrestricted Nurse Practitioner or Physician Assistant license in South Carolina with at least two years of clinical experience. Experience in Internal, Family, Primary, Urgent, or Emergency Medicine is required.
Market context
Advanced-practice roles in South Carolina are often competitive because employers look for licensed NPs or PAs with board certification, a master’s degree, and the flexibility to travel to assigned facilities. Candidates should expect demand for clinicians who can communicate clearly across care teams and adapt to different settings. On this platform, job requirements and benefits are AI-summarized from the original job description, saving you research time; before applying, verify your license, certification, and travel readiness match the posting.
