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  3. Clinical Nurse III - Medical Surgical 3rd Floor, FT, Days
CO

Clinical Nurse III - Medical Surgical 3rd Floor, FT, Days

City of Hope·Irvine, California

Full Time·On Site·2-5 yrs·Posted 6 days ago
Practice for this role

About the role

Coordinate and provide specialized oncology-focused care for patients with various medical-surgical conditions, including those undergoing chemotherapy. Perform comprehensive assessments, develop evidence-based care plans, and mentor new staff members within the unit.

Join the transformative team at City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses.

City of Hope’s growing national system includes its Los Angeles campus, a network of clinical care locations across Southern California, a new cancer center in Orange County, California, and treatment facilities in Atlanta, Chicago and Phoenix.

Our dedicated and compassionate employees are driven by a common mission: To deliver the cures of tomorrow to the people who need them today.

City of Hope Orange County is transforming cancer treatment by bringing world-class expertise and specialized care closer to home.

Supported by a regional network of care, our 11-acre academic cancer campus in Irvine is home to City of Hope Orange County Lennar Foundation Cancer Center, our outpatient cancer center, and Orange County’s only cancer specialty hospital is now open serving the community.

Are you an experienced Medical Surgical nurse looking for an opportunity to make a real difference in the lives of cancer patients?

Join our team at City of Hope Orange County Cancer Specialty Hospital as a Clinical Nurse III in the Medical Surgical Unit and be part of a groundbreaking team dedicated to providing world-class, compassionate care to a diverse range of patients.

As a Clinical Nurse III, you will play a vital role in guiding and coordinating care for a diverse range of patients, including those with cardiac, respiratory, sepsis, diabetes, and post-surgical conditions, many of whom are undergoing chemotherapy and other cancer-related treatments.

You will provide specialized oncology-focused care, ensuring the highest standards of treatment in accordance with Nursing Department policies and procedures.

This role includes performing comprehensive assessments, monitoring treatment-related side effects and post-operative complications, and developing individualized, evidence-based care plans.

You will collaborate closely with physicians, pharmacists, and interdisciplinary teams to support patients throughout active treatment and recovery, directly impacting outcomes and quality of life.

We are looking for passionate, skilled nurses who can think critically, act decisively, and provide compassionate support to patients and families.

Your ability to effectively communicate, document, and integrate cultural, psychosocial, and spiritual needs into care plans will be key to delivering exceptional care.

As a successful candidate, you will: Utilizes the nursing process and practice standards as a framework for the management of patient care.

Can assess patient conditions, recognize early signs of complications, and respond effectively.

Delegates to licensed and unlicensed personnel.

Demonstrates knowledge of the clinical information system and applies principles to patient documentation.

Prioritizes holistic care, addressing both the physical and emotional needs of the patients.

Serves as a mentor and role model to new staff members.

Integrates and practices according to the City of Hope Professional Practice Model to deliver care service excellence.

In alignment with City of Hope mission and values, the Division of Nursing and Patient Care Services vision and mission, and with continuous focus on the patient, family and community, carries out the nursing process, coordinates interdisciplinary care planning, documents according to standards, including validation of the patient and caregiver’s understanding of the plan of care and expected outcomes.

The nurse is a change agent, committed to lifelong learning, professional development and embodiment of City of Hope organizational mission and values, and the values and ethos of the profession of nursing.

20 bed unit Shift: Days Multiple Positions Available

Your qualifications should include

  • Bachelor’s Degree 3 – 5 years related experience Current CA Registered Nurse License Current Basic Life Support (BLS) through American Heart Association Current Advanced Cardiac Life Support (ACLS) through American Heart Association ONS chemotherapy/immunotherapy certification
  • City of
  • Hope employees pay is based on the following criteria: work experience, qualifications, and work location. City of Hope is an equal opportunity employer. To learn more about our Comprehensive Benefits, please CLICK HERE.

Requirements

Requires a Bachelor's degree, 3-5 years of related experience, and a current California Registered Nurse license. Must hold BLS, ACLS, and ONS chemotherapy/immunotherapy certifications.

  • bachelor degree
  • professional certificate
  • Care Planning
  • Patient Monitoring
  • Mentoring
  • Patient Assessment
  • Clinical Documentation
  • Critical Thinking
  • Holistic Care
  • Interdisciplinary Collaboration
  • Oncology Nursing
  • Chemotherapy Administration

Posting details

Employment type
Full Time
Work arrangement
On Site
Experience
2-5 yrs
Location
Irvine, California
Posted
Jul 22, 2026
Application
Employer website
CO

Hiring organization

City of Hope

City of Hope's mission is to deliver the cures of tomorrow to the people who need them today. Founded in 1913, City of Hope has grown into one of the largest cancer research and treatment organizations in the U.S. and one of the leading research centers for diabetes and other...

Salary listed on 45 jobs
IndustryHospitals and Health Care
TypeNonprofit
Size10,001+ employees
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Market context

California nursing roles remain highly competitive

California nursing roles often draw steady demand, especially for experienced RNs in procedural and critical care settings. Competition is strongest for candidates who already hold a California RN license, current BLS and ACLS, and recent ICU, ER, or PACU experience. Review the AI-summarized requirements and benefits on this platform to save research time, then confirm your certifications and highlight relevant bedside and procedural experience in your application.

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