Mass General Brigham·Boston, Massachusetts
The fellow will lead a mentored research project focused on the molecular mechanisms of inherited retinal degenerative diseases and the development of genetic therapies. Responsibilities include designing experiments, analyzing genomic and imaging data, and contributing to scientific manuscripts and presentations.
Site: Massachusetts Eye and Ear Infirmary
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Job Summary Proposes and undertakes a mentored, innovative project or challenge to develop novel techniques for Ophthalmic Treatments. Designs and performs experiments, analyzes and presents the outcome.
Qualifications: Education MD/PhD or equivalent
$70,000.00 - $71,750.00/Annual
Additional Job Details (if applicable)
The Chekuri Lab is seeking a postdoctoral fellow to join an NIH-funded research program focused on understanding the molecular mechanisms of inherited retinal degenerative diseases and developing genetic therapies for these conditions. The project uses mouse models, retinal cell and molecular biology approaches, ocular genomics, and AAV-based strategies to study disease mechanisms and evaluate therapeutic approaches. The postdoctoral fellow will lead a mentored research project involving in vitro and in vivo experiments, molecular and functional outcome analyses, data presentation, manuscript preparation, and collaborative project development. This position is a good fit for a candidate interested in retinal degeneration, ocular genomics, gene therapy, and translational vision research. The lab is based at the Schepens Eye Research Institute in the Grousbeck Gene Therapy Center and has close associations with the Ocular Genomics Institute and the Department of Ophthalmology at Harvard Medical School. The fellow will be part of a highly collaborative vision research community with access to resources in retinal disease genetics, ocular gene therapy, genomics, imaging, animal models, and translational research. ESSENTIAL FUNCTIONS: Review and summarize relevant literature in retinal degeneration, ocular genomics, and gene therapy. Design, perform, and troubleshoot in vitro and in vivo experiments. Work with mouse models, retinal/RPE tissues, cell-based systems, and molecular biology assays. Analyze molecular, histological, imaging, functional, and genomic data. Maintain organized experimental records, protocols, and data files. Meet regularly with the mentor to review progress and project milestones. Present findings in lab meetings, seminars, conferences, and project discussions. Contribute to manuscripts, abstracts, posters, reports, and grant-related materials. Attend ARVO meetings, seminars, and training opportunities. EDUCATION AND EXPERIENCE: Doctoral degree (MD or PhD) WORKING CONDITIONS: Lab setting. PHYSICAL REQUIREMENTS: Possible lifting of 10 to 20 lbs., depending on nature of chosen project(s). HIPAA Privacy Training and Sanctions All employees who have access to health information whose confidentiality is protected by the HIPAA Privacy Rule are required by the Rule to receive training so that they have an understanding and knowledge of the Privacy Rule that corresponds to their job responsibilities and of the group health plan’s policies and procedures that impact on their job duties. Training on the requirements of the HIPAA Privacy Rule and the plan’s health information policies and procedures under the direction of the institution’s privacy officer is a pre-requisite for this position. Employees who violate the requirements of the HIPAA Privacy Rule will be subject to discipline, up to and including termination. This description is intended to indicate essential tasks and levels of work difficulty that will be required of positions that will be given this title. It is not intended to limit or in any way modify the right of supervisors to assign, direct, or control the work of staff members under their supervision. The use of a particular expression or illustration describing duties shall not be held to exclude other duties not mentioned but that are of similar kind or level of difficulty.
Work Location 20 Staniford Street: Scheduled Weekly Hours 40
Employee Type Regular: Work Shift Day (United States of America)
5110 Massachusetts Eye and Ear Infirmary is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.
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A doctoral degree (MD or PhD) is required for this position. Candidates must have the ability to work in a lab setting and perform physical tasks such as lifting 10 to 20 lbs.
Market context
In Massachusetts, Research Fellow PGY 4 roles are typically driven by academic medical centers, research institutes, and hospital-based labs that need doctoral-level support for ongoing studies. Competition is often shaped by prior research experience, comfort in a lab setting, and the ability to handle physical tasks such as lifting 10 to 20 lbs. Job requirements and benefits on this platform are AI-summarized from the original job description, saving you time on research; review the full posting closely and tailor your application to the specific lab focus.