The scientist will design and conduct research on epitranscriptomic mechanisms regulating cardiac development and congenital heart disease. Responsibilities include analyzing data, publishing findings in peer-reviewed journals, and working toward research independence.
Requirements summary
A PhD or equivalent degree in a relevant scientific field is required. Candidates must have research experience from their PhD program and possess strong laboratory technical and computer skills.
Dr. Jihyun Jang at Nationwide Children’s Hospital and The Ohio State University is seeking a Fellow to study how epitranscriptomic mechanisms regulate cardiac development and congenital heart disease. Our research focuses on m6A RNA methylation and its roles in developmental cell fate decisions, congenital heart defects, and pediatric cardiomyopathies. Using human iPSC-derived cardiac organoids, genetically engineered mouse models, CRISPR technologies, and single-cell/multi-omics approaches, we investigate the molecular regulation of heart development and disease. Projects include ventricular development, congenital valve disease, endocardial biology, and pediatric cardiomyopathy.
Read more about the lab here: Jihyun Jang
Job Description
Summary: Conducts research, designs experiments, analyzes data, and presents findings under the mentorship of an established RI principal investigator or Senior Research Scientists. Appointment is a maximum of 7 years in length.
Job Description
Essential Functions: Designs experiments, develops protocols, and conducts research under the guidance of a faculty mentor. Assists in the training and supervision of technical support staff in performing specific techniques essential to carrying out the research program. Records and analyzes data generated by the research study. Assists in the development of hypotheses for further investigation from the results of the studies performed. Assists with the preparation of scientific and technical papers for publication in peer-reviewed journals. Presents findings at local and national research forums. Collaborates with other ongoing research efforts either at NCH or at The Ohio State University. Works toward research independence, preparing to submit proposals to and obtain funding from external granting agencies. Education Requirement: PhD or equivalent degree in relevant field of science, required. Licensure Requirement: (not specified) Certifications: (not specified) Skills: Effective interpersonal skills required in interactions with scientists, physicians, and laboratory colleagues. Excellent laboratory technical skills. Excellent computer skills. Skills in qualitative and quantitative research methods. Ability to proactively manage and drive projects.
Experience
Research experience from PhD program, required.
Physical
Requirements:
Occasionally:
Bend/twist,
Climb stairs/ladder,
Lifting /
Carrying: 11-20 lbs
Frequently:
Lifting /
Carrying: 0-10 lbs,
Standing,
Walking
CONTINUOUSLY: Audible speech, Color vision, Computer skills,
Requirements performed but not listed above: Pressure in this position will vary depending on the workload. The workload will be heavy but manageable most of the time. Pressure may arise in the face of deadlines associated research and manuscript writing. "The above list of duties is intended to describe the general nature and level of work performed by individuals assigned to this classification. It is not to be construed as an exhaustive list of duties performed by the individuals so classified, nor is it intended to limit or modify the right of any supervisor to assign, direct, and control the work of employees under their supervision. EOE M/F/Disability/Vet" The moment you walk through our doors, you feel it. When you meet our patient families, you believe it. And when you talk with anyone who works here, you want to be part of it. Welcome to Nationwide Children’s Hospital, Where Passion Meets Purpose. Here, Diversity, Equity and Inclusion are integrated into our core values and practices. We are passionate about building, sustaining and evolving an inclusive and equitable environment. We are seeking individuals who live these values and want to share their experiences and efforts in support of our collective mission. We’re 15,000 strong. And it takes every one of us to improve the lives of the kids we care for, and the kids around the world we’ll never meet. Kids who live healthier, fuller lives because of the knowledge we share. We know it takes a Collaborative Culture to deliver on our promise to provide the very best, innovative care and to foster new discoveries, made possible by the most groundbreaking research. Anywhere. Ask anyone with a Nationwide Children’s badge what they do for a living. They’ll tell you it’s More Than a Job. It’s a calling. It’s a chance to use and grow your talent to make an impact that truly matters. Because here, we exist simply to help children everywhere. Nationwide Children’s Hospital. A Place to Be Proud.